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Coli, Campylobacter jejuni, and Shigella bacteria Co-trimoxazole: learn about side effects, dosage, special Online Clinical Nurse Specialist Programs precautions, Co-trimoxazole is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the urinary tract, ears, and intestines. It is sold as Bactrim® (manufactured by Roche) or Septra® (by Monarch Pharmaceuticals). 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